PROGRAM

São Paulo School of Advanced Science on Molecular Basis of Inflammatory Diseases

04th - 14th November 2019

MONDAY, 04th November 2019

REGISTRATION, OPENING & KEYNOTE LECTURE

14:00 – 16:30     Arrival, Registration and Poster placing

17:30 – 17:45     Opening Ceremony

Organizing Committee

17:45 – 18:30     FAPESP Presentation  

Speaker: Prof.  Hernan Chaimovich

18:30 – 19:30     Opening Lecture: Immunometabolism at the heart of immunity and                                                   inflammation

Speaker: Luke O’Neill, Trinity Biomedical Sciences Institute, Ireland

Discussion Leader: José C. Alves-Filho

19:30 – 22:00      Welcome Reception   

19:30 – 22:00      Dinner

TUESDAY, 05th November 2019

SESSION I: METABOLIC CONTROL OF INFLAMMATION

Discussion Leader: José C. Alves-Filho

09:00 – 10:00    Macrophage responses to dead cells: drives of functional polarization

Larissa Cunha, FMRP, University of São Paulo, Brazil

10:00 – 10:30    Coffee Break

10:30 – 11:30 Sirtuin 1 and cell metabolism in innate and adaptive cells

Niels O. Camara, ICB, University of São Paulo, Brazil

11:30 – 12:30   Metabolic checkpoints controlling immune cell function

Tim Sparwasser, University of Mainz, Germany       

12:30 – 14:00     Lunch

15:30 – 16:30     How to conduct translational research in 21st century 

Speaker: Yang Xia, University of Texas, USA

Discussion Leader: Rita Tostes

17:00 – 19:30     Poster Session I

17:00 – 19:30      Social Hour with beer*

19:30 – 22:00      Dinner

WEDNESDAY, 06th November 2019

SESSION II: INFLAMMATORY RESPONSES DURING INFECTIOUS DISEASES

Discussion Leader: Fernando Q. Cunha

09:00 – 10:00    IL-17, the microbiome and susceptibility to autoimmunity

Ari Waisman, University of Mainz, Germany

10:00 – 10:30    Coffee Break

10:30 – 11:30    Lessons from Leishmania persistence: tissue resident macrophages as                                           replicative niches for intracellular pathogens.

David Sacks, NIAID, National Institutes of Health, USA

11:30 – 12:30     Host response to pathogens, pathobionts and comensals: Resistance and                                          Tolerance

Marcelo Bozza, Federal University of Rio de Janeiro, Brazil

12:30 – 14:00     Lunch

15:30 – 16:30    Animal models for translational research of inflammatory diseases I

Speakers: Marcelo Bozza, Federal University of Rio de Janeiro, Brazil       

                    David Sacks, NIAD, National Institutes of Health, USA

Discussion Leader: Fernando Q. Cunha

17:00 – 19:30     Poster Session II

17:00 – 19:30     Social Hour with beer*

19:30 – 22:00      Dinner

THURSDAY, 07th November 2019

SESSION III: MOLECULAR BASIS OF NEURO-INFLAMMATION

Discussion Leader: Thiago M. Cunha

09:00 – 10:00   The circadian cycle in malaria: the sweet side of the story

Ricardo T. Gazzinelli, FIOCRUZ, Brazil

10:00 – 10:30    Coffee Break

10:30 – 11:30    Extra-pineal melatonin as a regular mediator of defense responses

Regina P. Markus, ICB, University of São Paulo, Brazil

11:30 – 12:30    Zika virus and immunopathogenesis in murine experimental model

Jean Pierre Peron, ICB, University of São Paulo, Brazil

12:30 – 14:00     Lunch

15:30 – 16:30    Animal models for translational research of inflammatory diseases II

Speaker: Jean Pierre Peron, ICB, University of São Paulo, Brazil

Discussion Leader: Thiago M. Cunha

17:00 – 19:30     Poster Session III

17:00 – 19:30    Social Hour with beer*

19:30 – 22:00    Dinner

FRIDAY, 08th November 2019

SESSION IV: MODULATING INFLAMMATION FOR CANCER THERAPY

Discussion Leader: Helder Nakaya

09:00 – 10:00    Molecular regulation of lymphocyte activation

Joao B. Viola, Brazilian National Cancer Institute, Brazil

10:00 – 10:30    Coffee Break

10:30 – 11:30    Control of CD4 T cell responses by dendritic cell NLRC4 in cancer and                                              infection

Fayyaz S. Sutterwala, Cedars-Sinai Medical Center, USA

11:30 – 12:30    Can anti-PD1 therapy directly affect innate cells?

Cristina Bonorino, Federal University of Health Sciences of Porto Alegre, Brazil

12:30 – 14:00     Lunch

15:00 – 18:00    Poster Session IV

18:30 – 22:00    Happy Hour at Toca do Urso – Colorado Brewery

(Participants must purchase their own ticket to attend)

19:30 – 22:00    Dinner

SATURDAY, 09th November 2019

SESSION V: MOLECULAR MECHANISMS OF MUCOSAL INFLAMMATION

Discussion Leader: Paulo Louzada Jr.

09:30 – 10:30      The IL-23/IL-22 axis in neonatal inflammation

Sergio Lira, Icahn School of Medicine at Mount Sinai, USA

10:30 – 11:30      In vitro differentiated memory cells as a tool  for immunotherapy

Joao B. Viola, Brazilian National Cancer Institute, Brazil

12:00 – 14:o0     Lunch

Afternoon            Sport Activities

19:30 – 22:00     Dinner

SUNDAY, 10th November 2019

Morning              Tour to the Candido Portinari House Museum in Brodowski city

(Booking required)

Morning              Free

12:00 – 15:00    Social Hour with Barbecue*

Afternoon           Sport Activities

19:30 – 22:00    Dinner

MONDAY, 11th November 2019

SESSION VI: INFLAMMATION AND CARDIOVASCULAR DISEASES

Discussion Leader: Rita Tostes

09:00 – 10:00    Immune mechanisms in hypertension

Ernesto L. Schiffrin, McGill University, Canada

10:00 – 10:30    Coffee Break

10:30 – 11:30    Vascular toxicity of anti-cancer drugs – implications in hypertension

Rhian M. Touyz, University of Glasgow, UK

11:30 – 12:30    Inflammation, autoimmunity and preeclampsia

Yang Xia, University of Texas, USA

12:30 – 14:00     Lunch

15:30 – 16:30    Career progression and what it takes to succeed

Speakers: Rhian M. Touyz, University of Glasgow, UK

Discussion Leader: Rita Tostes

16:30 – 17:00    Coffee Break

19:30 – 22:00    Dinner

TUESDAY, 12th November 2019

SESSION VII: MOLECULAR MECHANISMS IN INNATE IMMUNITY

Discussion Leader: Larissa Cunha

09:00 – 10:00    Apoptotic and non-apoptotic functions of caspases in host defense

Sunny Shin, University of Pennsylvania, USA

10:00 – 10:30    Coffee Break

10:30 – 11:30     Immunometabolic functions of lipid droplets in host response to infections

Patricia T. Bozza, FIOCRUZ, Brazil

11:30 – 12:30     Innate immune defense against intracellular bacterial pathogens

Igor Brodsky, University of Pennsylvania, USA

12:30 – 14:00     Lunch

15:30 – 16:30     The Center for Research in Inflammatory Diseases (CRID)

Fernando Q. Cunha, CRID USP, Brazil 

16:30 – 17:00  Coffee Break

19:30 – 22:00  Dinner

WEDNESDAY, 13th November 2019

SESSION VIII: MEDIATORS OF INFLAMMATION

Discussion Leader: João Santana Silva

09:00 – 10:00     Schistosoma mansoni surface proteins: anti-inflammatory properties and                                     potential molecules for therapeutics

Sergio Costa Oliveira, Federal University of Minas Gerais, Brazil

10:00 – 10:30    Coffee Break

10:30 – 11:30    Inflammasomes in host response to infectious diseases

Dario Zamboni, CRID USP, Brazil

11:30 – 12:30   Inflammation, microbiota and infection

Mauro M. Teixeira, Federal University of Minas Gerais, Brazil

12:30 – 14:00     Lunch

14:30 – 15:30      Single-cell transcriptome sequencing

Presentation sponsored by Pensabio

15:30 – 18:30    Visit to the USP – Campus Ribeirão Preto

19:30 – 22:00    Dinner

THURSDAY, 14th November 2019

06:00 – 8:30    Breakfast

07:00 – 8:30    Departure

* Alcohol served at this function is not subsidized by FAPESP. Funding for this expense is provided by other revenue sources.